Biosafety Levels Explained

Biosafety Level 1

Suitable for work involving well-characterized agents not known to cause disease in health adult humans and of minimal potential hazard to laboratory personnel and the environment

  • Examples
    • Bacillus subtilis
    • Bacillus cerculans
    • Escherichia coli, (non-pathogenic strains such as K-12)

 

Biosafety Level 2

Suitable for work involving agents of moderate potential hazard to personnel and the environment, immunization or antibiotic treatment is available in the event of exposure.

  • Examples
    • Measles Virus
    • Hepatitis B Virus
    • Staphylococcus aureus
    • Clostridium perfringens
    • Salmonellae, such as S. tyhpi

Note: All work involving the use of cultured human an animal cell lines, according to the University of Arizona's Biosafety Manual must be conducted at Biosafety Level 2.

 

Biosafety Level 3

Suitable for work involving agents which may cause serious or protentially lethal disease as a result of exposure by the inhalation route with serious potential hazard to personnel and the environment. There are no available vaccines or therapeutic treatments available.

  • Examples
    • Mycobacterium tuberculosis
    • Coccidioides immitis
    • Brucella melitensis
    • St. Louis encephalitis virus
    • HIV-1