Biosafety Levels Explained
Biosafety Level 1
Suitable for work involving well-characterized agents not known to cause disease in health adult humans and of minimal potential hazard to laboratory personnel and the environment
- Examples
- Bacillus subtilis
- Bacillus cerculans
- Escherichia coli, (non-pathogenic strains such as K-12)
Biosafety Level 2
Suitable for work involving agents of moderate potential hazard to personnel and the environment, immunization or antibiotic treatment is available in the event of exposure.
- Examples
- Measles Virus
- Hepatitis B Virus
- Staphylococcus aureus
- Clostridium perfringens
- Salmonellae, such as S. tyhpi
Note: All work involving the use of cultured human an animal cell lines, according to the University of Arizona's Biosafety Manual must be conducted at Biosafety Level 2.
Biosafety Level 3
Suitable for work involving agents which may cause serious or protentially lethal disease as a result of exposure by the inhalation route with serious potential hazard to personnel and the environment. There are no available vaccines or therapeutic treatments available.
- Examples
- Mycobacterium tuberculosis
- Coccidioides immitis
- Brucella melitensis
- St. Louis encephalitis virus
- HIV-1